Advanced Research on Animal Cell Technology

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Advanced Research on Animal Cell Technology
  • 书名: Advanced Research on Animal Cell Technology
  • 作者: Alain O.A. Miller
  • ISBN: 9789401068819
  • 出版时间: 2011-10-28
  • 出版社: Springer
  • 入库时间: 1486284068
  • 更新时间: 1486284068
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内容简介

目录I.Cell-CellCommunicationandCellExtracellularMatrixInteractions.-ExtracellularMatrixCellDifferentiation.-StructureandFunctionoftheHeparanSulfateProteoglycans.-RolePlayedbyGapJunctionsinCell-CellCommunication.-Fibronectin-MediatedCellular(Inter)actions.-II.“Normal”Versus“Abnormal”Cells.-UseofCellLinesinBiotechnology.-WhyNotUsePrimaryCells.-III.LargeScaleCultivationofAnimalCells.-TechnologyofMassCultivation:AnOverview.-CellCultureinHollowFibreBioreactors.-PerfusionCulture.-GoodManufacturingPracticeintheProductionofBiologicalsbyCellCultures.-Biosensors.-IV.AnalysisoftheCell’sBehaviour.-EffectsofRetinoidsonGrowthDifferentiation.-PhosphoinositideMetabolismandControlofCellProliferation.-SomaticCellGeneticAnalysisofGrowthControl.-PromoterOrganizationofEukaryoticProtein-CodingGenes.-V.ModificationoftheCellGenome.-TailoringofanAnti-HumanPlacentalAlkalinePhosphataseImmunoglobulinUsingGeneticEngineering.-VacciniaVirusasanExpressionVector.-ExpressionandIntegrationofExogenousDNASeguencesTransfectedintoMammalianCells.-CooperationofOncogenesinMalignantTransformation.-VI.ApplicationsofAnimalCellCultures.-MolecularDissectionoftheCellCycle.-UseofMicrobeadsforCellTransplantation.-InfluenceofEpigeneticFactorsonEpidermalDifferentiationandMorphogenesis.-TheCharacterizationofFibroblastGrowthFactorandItsBiologicalEffectInVitroandInVivo.-CultureofHybridomas―ASurvey.-ApplicationsofChromatographyinDownstreamProcessing.-Generaldiscussion.I.Cell-CellCommunicationandCellExtracellularMatrixInteractions.-ExtracellularMatrixCellDifferentiation.-StructureandFunctionoftheHeparanSulfateProteoglycans.-RolePlayedbyGapJunctionsinCell-CellCommunication.-Fibronectin-MediatedCellular(Inter)actions.-II.“Normal”Versus“Abnormal”Cells.-UseofCellLinesinBiotechnology.-WhyNotUsePrimaryCells.-III.LargeScaleCultivationofAnimalCells.-TechnologyofMassCultivation:AnOverview.-CellCultureinHollowFibreBioreactors.-PerfusionCulture.-GoodManufacturingPracticeintheProductionofBiologicalsbyCellCultures.-Biosensors.-IV.AnalysisoftheCell’sBehaviour.-EffectsofRetinoidsonGrowthDifferentiation.-PhosphoinositideMetabolismandControlofCellProliferation.-SomaticCellGeneticAnalysisofGrowthControl.-PromoterOrganizationofEukaryoticProtein-CodingGenes.-V.ModificationoftheCellGenome.-TailoringofanAnti-HumanPlacentalAlkalinePhosphataseImmunoglobulinUsingGeneticEngineering.-VacciniaVirusasanExpressionVector.-ExpressionandIntegrationofExogenousDNASeguencesTransfectedintoMammalianCells.-CooperationofOncogenesinMalignantTransformation.-VI.ApplicationsofAnimalCellCultures.-MolecularDissectionoftheCellCycle.-UseofMicrobeadsforCellTransplantation.-InfluenceofEpigeneticFactorsonEpidermalDifferentiationandMorphogenesis.-TheCharacterizationofFibroblastGrowthFactorandItsBiologicalEffectInVitroandInVivo.-CultureofHybridomas―ASurvey.-ApplicationsofChromatographyinDownstreamProcessing.-Generaldiscussion.

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